منابع مشابه
Micronuclei and pesticide exposure.
Micronucleus (MN) is a biomarker widely used in biomonitoring studies carried out to determine the genetic risk associated to pesticide exposure. Many in vitro and in vivo studies, as well as epidemiological approaches, have demonstrated the ability of certain chemical pesticides to produce genetic effects including cancer and other chronic pathologies in humans; thus, biomonitoring studies hav...
متن کاملEnvironmental lead exposure increases micronuclei in children.
The objective of this pilot study was to investigate the contribution of environmental exposures to lead in the development of cytogenetic damage detected as the frequency of micronuclei (MN) in children. The other aim was to apply the MN assay in combination with fluorescence in situ hybridization (FISH) using a pan-centromeric chromosome probe to elucidate the formation mechanism of induced M...
متن کاملPesticide exposure in children.
Pesticides are a collective term for a wide array of chemicals intended to kill unwanted insects, plants, molds, and rodents. Food, water, and treatment in the home, yard, and school are all potential sources of children's exposure. Exposures to pesticides may be overt or subacute, and effects range from acute to chronic toxicity. In 2008, pesticides were the ninth most common substance reporte...
متن کاملPesticide exposure and sprayer design: ergonomics evaluation to reduce pesticide exposure.
Plant protection products are used in agriculture to improve yields, but this use can cause contamination of the environment and is also likely to have adverse short and long term effects on agricultural workers. This poster describes a systems approach to reducing the risk of operator exposure to plant protection products through the introduction of ergonomics to the design process of large ag...
متن کامل[Micronuclei and genetic polymorphisms: from exposure to susceptibility].
The concept of genetic susceptibility and interactions between genetic and environmental factors of risk is a new trend in molecular epidemiology studies of cancers. Micronuclei are biomarkers of chromosome damage due to genetic instability or exposure to environmental mutagens or carcinogens. The micronucleus assay in combination with fluorescent in situ hybridization discriminates between mic...
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ژورنال
عنوان ژورنال: Mutagenesis
سال: 2010
ISSN: 0267-8357,1464-3804
DOI: 10.1093/mutage/geq070